Scientific Studies

What do the studies say about Reishi, Turkey Tail, Lions Mane, Cordyceps, Chaga and Tremella mushrooms?

Turkey Tail mushroom*

  • Reishi mushroom and dopamine support [1]
  • Reishi mushroom and immune support [2]
  • Reishi mushroom and cancer support [7]
  • Reishi mushroom and brain injuries [13]
  • Reishi mushroom and renal support [14]
  • Reishi mushroom and the central nervous system [11]
  • Turkey tail mushroom and immune support [3]
  • Turkey tail mushroom and digestion support [4]
  • Turkey tail mushroom and cancer support [8]
  • Turkey tail mushoom human trial for cancer patients [9]
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Lions Mane mushroom*

  • Lion's mane mushroom appears to promote neuronal prolongation and formation of myelin[21] 
  • One human study using 3g of 98% lion's mane powder showed significantly improvements on a rating scale of dementia in persons suffering from general cognitive decline.[25] 
  • Neuroregenerative potential of lion's mane mushroom [29] 
  • Potential reduction of depression and anxiety by 4 weeks Hericium erinaceus intake [31] 
  • Nerve growth factor-inducing activity of Hericium erinaceus [32]

Cordyceps sinensis*

  • Cordyceps and Endurance benefits on mice [15] 
  • A 2010 study suggests that supplementation with Cs-4 (Cordyceps sinensis) improves exercise performance and might contribute to wellness in healthy older subjects. [24] 
  • Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators [17] 
  • Cordyceps sinensis Cs-5 enhances sexual functions in normal and impotent models [18] 
  • Cordyceps sinensis Cs-5 improves memory and learning abilities in a dysmnesia model [19] 
  • Protective effects of Cordyceps sinensis and exercise training on septic shock [20]

Chaga mushroom*

  • Chaga and cancer support [1]
  • Chaga and lung cancer [2]
  • Assessment of the Gastroprotective Effect of the Chaga Mushroom [4]
  • Chaga on brain function and learning [5]
  • Chaga may also have antidiabetic effects (27)
  • In animal models, chaga displayed anti-allergic (17), cognition-enhancing, and antioxidant activities (18); as well as anti-inflammatory effects against experimental colitis (19)

Tremella fuciformis*

  • Tremella benefits (14) 
  • White fungus polysaccharides may protect brain cells against nerve cell damage and degenerative diseases (17) 
  • One test-tube study found that white fungus extract may reduce brain toxicity caused by beta-amyloid — a protein that in high amounts has been linked to the development of Alzheimer’s disease (18) (19) 
  • Research also suggests that the extract may improve memory. One 8-week study in 75 people found that consuming either 600 mg or 1,200 mg of a white fungus supplement per day improved memory questionnaire scores — especially in short-term memory parameters — compared with a control group (20) 
  • Similarly, one 14-day study in rats showed that a daily oral treatment with white fungus extract significantly reversed drug-induced memory loss (21) 
  • Tremella extract efficiently enhances mouse fatigue endurance and anti-hypoxia capability partly through energy reserves and antioxidant enzyme activity. (29) 
  • Tremella mushroom and traditional Chinese medicine [25] 
  • Tremella’s polysaccharides may improve skin hydration by reducing water and collagen losses in the skin after sun or ultraviolet exposure (24) 
  • Protective effect of polysaccharides isolated from Tremella fuciformis against radiation-induced damage in mice (31) 
  • Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial (33)
  • Tremella fuciformis enhances the neurite outgrowth in rats (34)
  • Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging and skin health (37)

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